∙ 诊疗指南 ∙骨肉瘤临床循证诊疗指南【摘要】骨肉瘤是常见的原发恶性骨肿瘤,严重危害青少年的身体健康。通过规范的化疗和手术,很多患者可达到痊愈,但不当的诊疗过程可能造成严重的不良后果。中国医师协会骨科医师分会骨肿瘤专业委员会依据循证医学方法制定了《骨肉瘤临床循证诊疗指南》,就诊断流程、化疗、不同部位的手术方式和挽救性治疗等临床问题进行总结,依据文献证据等级给出相应的推荐等级。旨在为骨肿瘤医师的临床诊疗提供最佳的、有效的意见参考,从而使患者达到最佳的治疗效果。本指南仅为学术性指导意见,具体实施时必须依据患者的个体医疗情况而定。【关键词】骨肉瘤骨肿瘤指南Guideline for clinical evidence based diagnosis⁃ and treatment of osteosarcomaMusculoskeletal Tumor Society, Chinese Association of Orthopaedic SurgeonsGUO Wei1*, NIU Xiaohui2*, XIAO Jianru3*, CAI Zhengdong4*(1.Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing 100044; 2.Department of Orthopaedic Oncology,Jishuitan Hospital, Beijing 100035; 3.Department of Orthopaedics, Shanghai Changzheng Hospital, Shanghai 200003;4. Department of Orthopaedics, Shanghai Central Hospital, Shanghai 200080, China)【Abstract 】 Osteosarcoma is a common primary malignancy of the bone and severely jeopardizes the health of teenagers. Standardized multi-modality treatment including chemotherapy and surgery can achieve cure of disease for many patients, while improper treatments could lead to severe consequences. The Musculoskeletal Tumor Society from Chinese Associa- tion of Orthopaedic Surgeons proposes the "Guideline for clinical evidence based⁃ diagnosis and treatment of osteosarcoma". This guideline addresses several clinical problems (e.g. diagnostic process, chemotherapy, surgical options for lesions of dif- ferent locations, and salvage treatments) and provides recommendations with categories of evidence and consensus. The aim of this guideline is to prov...